Transportation: Air | Bus | Train | Car | Foot Car The Greater Ypsilanti Area can be accessed via several major interstates, including: I-94: Exit at 183 - Huron Street - head north on Huron Street. This will take you to the Downtown, Depot Town Areas or to the campus of Eastern Michigan University. US-23: Exit at Washtenaw Avenue/Ypsilanti - head east on Washtenaw Avenue. For Downtown turn right at Hamilton. For Depot Town, continue east on Huron, then turn North to Cross Street. Cross Street will return you to westbound Washtenaw Avenue. US-12: Also known as Michigan Avenue. Ypsilanti is a major portion of the US-12/Michigan Avenue route. You can access Depot Town and Eastern Michigan University at the Michigan Avenue/Huron Street intersection. Ypsilanti can also be reached from adjoining interstates M-14, I-75 and I-275.